Tri-Luma® is an FDA-approved medication for the treatment of melanoma.

Tri-Luma® is applied to the skin to reduce the appearance of the dark spots and patches of melasma

Tri-Luma® contains 3 active ingredients, uniquely combined and more effective than treatments containing only one or two of the ingredients. Active ingredients include:

• Fluocinolone acetonide 0.01%. This is a mild corticosteroid that reduces inflammation.
• Hydroquinone 4%. This is a depigmenting agent that interrupts the formation and synthesis of melanin to help lighten the skin.
• Tretinoin 0.05%. This is a topical retinoid that works by increasing the skin cell turnover rate, which helps exfoliate the skin.

Tri-Luma® should always be used in conjunction with sun-avoidance measures, like using sunscreens and wearing protective clothing.

Tri-Luma® may improve the appearance of melasma but is not a cure.