Isotretinoin for Acne - Health Tips

Get practical tips regarding Isotretinoin for Acne to help you prepare for your appointments and manage your care from home.

Thoughts on Isotretinoin for Acne by Dr. Jeffrey Poole, MD, FAAD
January 2006
Isotretinoin is the active ingredient of several oral acne medication brands, including Accutane (now withdrawn from the market), Amnesteem, and Sotret.

Although there have been concerns raised about a range of possible side effects, isotretinoin continues to be prescribed for acne because of its unique benefits. Isotretinoin is by far our most effective therapy for acne, and has the potential to cure someone’s acne. It is a very safe medicine when properly prescribed, and virtually every patient I have treated with isotretinoin is thrilled with the results and lack of significant side effects.

Generally, isotretinoin has been thought of as a “last resort” treatment or for severe-nodular cystic acne. However, I prescribe isotretinoin in a wide variety of cases:
- for the persistent or resistant acne that is not responding well to standard treatments
- for the patient that is beginning to develop or at risk of developing acne scars
- for the patient with moderate but extensive acne at a young age with a family history of severe or scarring acne
- and often for the adult patient who has persistent moderate acne and is tired of all the creams and pills and wants a “cure”.

These are some of the most common reasons I use for starting isotretinoin, but I address each person individually regarding their acne and situation, and often present isotretinoin as one, excellent option.