Disease-modifying therapy (DMT) for multiple sclerosis (MS) is a type of treatment that aims to slow down the progression of the disease and reduce the frequency and severity of relapses. DMTs work by modifying the underlying disease process in MS, rather than just treating symptoms.
There are several different types of DMTs available for MS, each of which target different aspects of the disease. Some of the most commonly used DMTs include:
- Interferons: These drugs work by regulating the activity of the immune system, which can help to reduce inflammation and slow down the progression of the disease.
- Glatiramer acetate: This drug helps to reduce the activity of the immune system by mimicking a protein found in myelin, the protective coating that surrounds nerve fibers.
- Natalizumab: This drug prevents certain immune cells from crossing the blood-brain barrier, which can help to reduce inflammation and slow down the progression of the disease.
- Fingolimod: This drug works by preventing certain immune cells from leaving the lymph nodes, which can help to reduce inflammation and slow down the progression of the disease.
- Alemtuzumab: This drug works by targeting and killing certain immune cells, which can help to reduce inflammation and slow down the progression of the disease.
- Ocrelizumab: This drug works by targeting a specific type of immune cell that is involved in the damage caused by MS.
It's important to note that DMTs can have different side effects, and not everyone will respond to the same DMT. It's important to work with your doctor to determine the best DMT for you, taking into account your personal preference, the side effect profile, and your overall health.
It's also important to note that DMTs are not a cure for MS, but they can help slow the progression of the disease and reduce the frequency and severity of relapses.
Source: Vivacare
Last updated : 1/27/2023