When should I consider starting disease-modifying therapy for multiple sclerosis?

The decision to start disease-modifying therapy (DMT) for multiple sclerosis (MS) is usually based on the type and severity of the disease, as well as the person's individual needs and preferences. Some indications that DMT may be necessary include:

1. Relapsing-remitting MS (RRMS): DMTs are recommended for people with relapsing-remitting MS (RRMS) to help reduce the frequency and severity of relapses.
2. Active disease: DMTs are recommended for people with active disease, as determined by magnetic resonance imaging (MRI) or clinical examination.
3. High risk of disability: DMTs are recommended for people who are at high risk of developing disability, as determined by the Expanded Disability Status Scale (EDSS) score.
4. Rapidly evolving severe RRMS (RESRRMS): DMTs are recommended for people with rapidly evolving severe RRMS to help slow down the progression of the disease and reduce the risk of developing secondary progressive MS (SPMS).
5. Progressive forms of MS: DMTs are also available for some forms of progressive MS such as Secondary Progressive MS (SPMS) with active inflammation or primary progressive MS (PPMS)

It's important to note that not everyone with MS will need to start DMTs right away. In some cases, symptom management and rehabilitation may be sufficient to manage the disease. However, for those who meet the above criteria and have active disease, DMTs are recommended to help slow down the progression of the disease and reduce the risk of developing disability.

It's important to work closely with a healthcare professional who specializes in MS to determine the best treatment plan for you. They will take into consideration your type of MS, disease activity, and overall health before making a recommendation.

Source: Vivacare
Last updated : 1/27/2023

When should I consider starting disease-modifying therapy for multiple sclerosis? originally published by Vivacare