Biologic medications are a class of drugs that target specific molecules in the immune system that are involved in the inflammation and joint damage caused by rheumatoid arthritis (RA). They are typically used in people who have not had success with traditional disease-modifying anti-rheumatic drugs (DMARDs) or in those who have rapidly progressing disease.
The decision to use a biologic is usually based on the severity of the disease and how well the person responds to other treatments. Some indications that a biologic may be necessary include:
- Active, moderate-to-severe RA: Biologics are recommended for people with active, moderate-to-severe RA who have not had success with traditional DMARDs.
- Rapidly progressing disease: Biologics can help to slow the progression of joint damage in people with rapidly progressing disease.
- High disease activity: Biologics can be used to control high levels of inflammation and improve physical function in people with RA.
- Poor response to traditional DMARDs: Biologics are recommended for people who have not had success with traditional DMARDs, such as methotrexate or sulfasalazine.
- High risk of serious infection: Biologics can be used to control inflammation in people who are at high risk of serious infection.
It's important to talk to your doctor if you are concerned about your RA. They will take into consideration your symptoms, disease activity, response to previous treatments, and overall health before deciding whether a biologic is necessary. They will also discuss the potential risks and benefits of the medication and the best treatment options for you.
It's also important to note that biologics are powerful drugs that can have serious side effects, so it is important to be informed about the risks and benefits of these medications before starting treatment.
Source: Vivacare
Last updated : 1/27/2023