Immunosuppressants for Eczema

How do oral or injectable systemic immunosuppressants help eczema?

Azathioprine, cyclosporine, methotrexate, and mycophenolate mofetil are systemic immunosuppressants that:

  • Suppress the immune system
  • Reduce the inflammation

Important: If your doctor prescribed a topical medication to treat your eczema, make sure to use it as directed before you put on a moisturizer.

What do I need to know about immunosuppressants used to treat eczema?

  • Not specifically approved to treat eczema; sometimes used off-label for moderate-to-severe eczema.
  • Sometimes used as an alternative to phototherapy.
  • Very strong medications, developed for chemotherapy and to prevent organ rejection after transplants.
  • Require short-term use and regular blood test monitoring by a doctor.
    Side effects may include blood pressure and kidney or liver problems.

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Last updated : 2/6/2023

Immunosuppressants for Eczema originally published by Allergy & Asthma Network

Eczema